Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 10/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587408 | 0.89 | HCAR3 (0.36) | HCAR3HCAR2HTR7TNKSTSHR | |
| SCHEMBL14619731 | 0.84 | TNKS (0.37) | HCAR3HCAR2TNKS | |
| SCHEMBL7840377 | 0.81 | HTR7 (0.36) | HCAR3HCAR2HTR7TSHRCCR2 | |
| SCHEMBL7095750 | 0.71 | ADRA1A (0.52) | HCAR3HCAR2HTR7TSHRADRA1A | |
| SCHEMBL6082094 | 0.71 | ADRA1A (0.52) | HCAR3HCAR2HTR7TSHRADRA1A | |
| SCHEMBL6959819 | 0.71 | ADRA1A (0.52) | HCAR3HCAR2HTR7TSHRADRA1A | |
| SCHEMBL6964542 | 0.70 | TNKS (0.32) | HCAR3HCAR2TNKSADRA1AADRA1B | |
| SCHEMBL6227914 | 0.69 | MTOR (0.37) | HTR7TSHRADRA1AADRA1BADRA1D | |
| SCHEMBL6082708 | 0.69 | MTOR (0.37) | HTR7TSHRADRA1AADRA1BADRA1D | |
| SCHEMBL5660885 | 0.69 | MTOR (0.37) | HTR7TSHRADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MARZABADI MOHAMMAD R | 2007-02-22 | — | — | US | disclosed |
| US-7067534-B1 | Substituted anilinic piperidines as MCH selective antagonists | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| US-6727264-B1 | MELANIN CONCENTRATING HORMONE-1 RECEPTOR ANTAGONISTS; SLEEP, EATING, SEXUAL DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-27 | — | — | US | disclosed |
| US-20040038855-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043080-A1 | Substituted anilinic piperidines as MCH selective antagonists | MCHR1, MCHR2, MC1R | HCAR3 83/4885HCAR2 73/4885HTR7 128/4885 |
| US-20040038855-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | HCAR3 69/4885HCAR2 191/4885HTR7 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.