Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209916 | 0.86 | KMT2A (0.46) | KMT2ATSHRNAMPTNPY5RCKS1B | |
| SCHEMBL5204794 | 0.86 | KMT2A (0.46) | KMT2ATSHRNAMPTNPY5RCKS1B | |
| SCHEMBL5206599 | 0.77 | GBA1 (0.48) | KMT2ATSHRNPY5RMEN1 | |
| SCHEMBL5203241 | 0.76 | KDM1A (0.46) | KMT2AKCNH2KDM1AMAOBMEN1 | |
| SCHEMBL5203603 | 0.76 | CCR5 (0.43) | KMT2ANPY5RKCNH2KDM1AMAOB | |
| SCHEMBL6964170 | 0.75 | MAPK13 (0.43) | KMT2AKCNH2KDM1AMAOBMAOA | |
| SCHEMBL27986660 | 0.74 | RPS6KB1 (0.49) | PIM1NPY5RRPS6KB1KDM1AMAOB | |
| SCHEMBL5203558 | 0.72 | VCP (0.47) | KMT2APIM1KCNH2KDM1AMAOB | |
| SCHEMBL5206571 | 0.72 | VCP (0.43) | KMT2APIM1KCNH2KDM1AMAOB | |
| SCHEMBL5205247 | 0.72 | VCP (0.45) | KMT2APIM1KCNH2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1306085-A1 | 2-Cyclohexyl-4-phenyl-1H-imidazole derivatives as ligands for the neuropeptide Y5 receptor | Neurogen Corporation (US) | 2003-05-02 | — | — | EP | disclosed |