Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591822 | 0.83 | CYP19A1 (0.61) | CYP19A1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL237854 | 0.79 | CYP19A1 (0.59) | CYP19A1ALDH1A1GAAMAPT | |
| SCHEMBL26114650 | 0.79 | CYP19A1 (0.58) | CYP19A1ALDH1A1GAAMAPTLMNA | |
| SCHEMBL301328 | 0.78 | ALDH1A1 (0.61) | CYP19A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4829936 | 0.78 | CYP19A1 (0.57) | CYP19A1ALDH1A1GAAMAPT | |
| SCHEMBL13360708 | 0.77 | CYP19A1 (0.53) | CYP19A1CYP17A1 | |
| SCHEMBL6972606 | 0.77 | NAPRT (0.62) | CYP19A1CYP17A1 | |
| SCHEMBL304656 | 0.76 | CYP19A1 (0.63) | CYP19A1MAPT | |
| SCHEMBL7064034 | 0.76 | CYP19A1 (0.54) | CYP19A1ALDH1A1 | |
| SCHEMBL6957861 | 0.75 | L3MBTL1 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |