Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.59 |
| ▸ | ACHE | P22303 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TCF4 | P15884 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434487 | 0.79 | BCHE (0.76) | BCHEACHE | |
| SCHEMBL8434517 | 0.79 | BCHE (0.72) | BCHEACHE | |
| SCHEMBL20813012 | 0.78 | TCF4 (0.68) | MAPTTCF4CTNNB1NPC1MEN1 | |
| SCHEMBL6964974 | 0.78 | MAPT (0.61) | MAPTTCF4CTNNB1LOXL2CYP4F2 | |
| SCHEMBL25464938 | 0.77 | LOXL2 (0.68) | MAPTLOXL2CYP4F2CYP4A11NPC1 | |
| SCHEMBL25464823 | 0.77 | LOXL2 (0.68) | MAPTLOXL2CYP4F2CYP4A11NPC1 | |
| SCHEMBL30417629 | 0.77 | LOXL2 (0.68) | MAPTLOXL2CYP4F2CYP4A11NPC1 | |
| SCHEMBL25464582 | 0.77 | LOXL2 (0.59) | MAPTLOXL2CYP4F2CYP4A11NPC1 | |
| SCHEMBL25464630 | 0.77 | LOXL2 (0.59) | MAPTLOXL2CYP4F2CYP4A11NPC1 | |
| SCHEMBL8705459 | 0.77 | LOXL2 (0.56) | MAPTTCF4CTNNB1LOXL2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-B1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2003-01-22 | — | — | EP | disclosed |
| US-6005103-A | TREATMENT OF BACTERIAL AND VIRAL INFECTIONS AND DISEASES, INCLUDING AIDS | WARNER-LAMBERT COMPANY (US) | 1999-12-21 | — | — | US | disclosed |