SCHEMBL6970149

SCHEMBL6970149

CCOc1ccc2c(c1)O/C(=C/c1ccc3c(c1)OCO3)C2=O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
POLB P06746 2/20 0.61
ACHE P22303 1/20 0.60
PPARG P37231 2/20 0.59
PPARD Q03181 2/20 0.59
STK17B O94768 2/20 0.59
PPARA Q07869 1/20 0.56
MAOB P27338 2/20 0.55
CSNK2A2 P19784 1/20 0.53
CSNK2B P67870 1/20 0.53
CSNK2A1 P68400 1/20 0.53
KDM4E B2RXH2 1/20 0.52
LMNA P02545 1/20 0.52
MAPT P10636 1/20 0.52
HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970155 1.00 MEN1 (0.61) MEN1KMT2APOLBACHEPPARG
SCHEMBL6965017 0.93 ACHE (0.60) MEN1KMT2APOLBACHEPPARG
SCHEMBL6962114 0.91 PPARG (0.61) MEN1KMT2APOLBACHEPPARG
SCHEMBL6968934 0.91 MEN1 (0.59) MEN1KMT2APOLBACHEPPARG
SCHEMBL6968932 0.91 MEN1 (0.59) MEN1KMT2APOLBACHEPPARG
SCHEMBL6962119 0.91 PPARG (0.61) MEN1KMT2APOLBACHEPPARG
SCHEMBL6970228 0.89 PNLIP (0.57) MEN1KMT2APOLBACHEPPARG
SCHEMBL6970231 0.89 PNLIP (0.57) MEN1KMT2APOLBACHEPPARG
SCHEMBL6963947 0.89 PNLIP (0.59) MEN1KMT2APOLBACHEPPARG
SCHEMBL6963953 0.89 PNLIP (0.59) MEN1KMT2APOLBACHEPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0902022-B1 NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME DAIICHI SEIYAKU CO (JP) 2003-07-30 EP disclosed
US-6143779-A Benzofuranone derivatives and a method for producing them SNOW BRAND MILK PRODUCTS CO., LTD. (JP) 2000-11-07 US disclosed
EP-0902022-A1 NOVEL BENZOFURANONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SNOW BRAND MILK PRODUCTS CO., LTD. (JP) 1999-03-17 EP disclosed