SCHEMBL69651

SCHEMBL69651

Oc1ccc(Br)c(O)c1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.42
POLB P06746 1/20 0.41
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
RECQL P46063 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
APEX1 P27695 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
PIM1 P11309 1/20 0.38
PTPN1 P18031 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
NQO2 P16083 1/20 0.37
ALOX12 P18054 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL581815 0.81 CA1 (0.48) ALOX15ALDH1A1HPGDRECQLTDP1
SCHEMBL9237623 0.79 POLB (0.45) ALOX15POLBALDH1A1HPGDRECQL
SCHEMBL25414587 0.79 ALOX15 (0.43) ALOX15POLBALDH1A1HPGDKDM4E
SCHEMBL37621 0.79 ALOX15 (0.43) ALOX15ALDH1A1HPGDRECQLTDP1
SCHEMBL94834 0.79 ALOX15 (0.43) ALOX15POLBALDH1A1HPGDKDM4E
SCHEMBL30363595 0.77 CA1 (0.47) ALOX15ALDH1A1HPGDRECQLTDP1
SCHEMBL31392373 0.77 POLB (0.50) ALOX15POLBALDH1A1HPGDRECQL
SCHEMBL604518 0.77 POLB (0.50) ALOX15POLBALDH1A1HPGDRECQL
SCHEMBL28414394 0.77 CA1 (0.47) ALOX15ALDH1A1HPGDRECQLTDP1
SCHEMBL11328303 0.77 ALOX15 (0.42) ALOX15POLBALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12023393-B2 Polymerizable 4,4′-spirobi[chromane]-2,2′-diones and curable compositions including the same SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-02 US disclosed
US-20240122815-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2024-04-18 US disclosed
EP-4308571-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME 3M Innovative Properties Company (US) 2024-01-24 EP disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
US-11835860-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-05 US disclosed
WO-2022195364-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-09-22 WO disclosed
US-20220026804-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-01-27 US disclosed
EP-3877447-A1 COMPOSITION OF PHTHALONITRILE RESIN MATRIX FOR POLYMER COMPOSITE MATERIALS, METHOD FOR FABRICATION THEREOF, METHOD FOR MANUFACTURING OF POLYMER COMPOSITE MATERIAL, AND MATERIAL OBTAINED BY THIS METHOD Joint Stock Company (RU) 2021-09-15 EP disclosed
CN-106029721-B Polymerizable composition containing reactive silsesquioxane compound 日产化学工业株式会社 2018-11-09 CN disclosed
US-9981887-B1 Synthesis of phenylethynylbenzenes THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2018-05-29 US disclosed
EP-0664014-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS Akzo Nobel N.V. (NL) 1995-07-26 EP disclosed
WO-1994008269-A1 NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS AKZO NOBEL N.V. (NL) 1994-04-14 WO disclosed
US-4661601-A PHOTOGRAPHIC BLACK COLOR COUPLER CIBA-GEIGY AG (CH) 1987-04-28 US disclosed
US-4493910-A COPOLYMER OF UNSATURATED AMIDE, N-VINYL LACTAM, UNSATURATED CARBOX KELVIN LENSES LIMITED (GB) 1985-01-15 US disclosed
EP-0069066-B1 RESORCINOLS AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1984-10-03 EP disclosed
US-4433111-A CONTACT LENSES, EXTENDED WEAR KELVIN LENSES LIMITED (GB) 1984-02-21 US disclosed
EP-0069066-A1 Resorcinols and their preparation CIBA-GEIGY AG (CH) 1983-01-05 EP disclosed
EP-0050934-A1 Fluorine-containing hydrogel-forming polymeric materials KELVIN LENSES LIMITED (GB) 1982-05-05 EP disclosed
US-4156663-A 260/857 R KANEBO, LTD. (JP) 1979-05-29 US disclosed
US-4072658-A FLAME RETARDANTS KANEBO, LTD. (JA) 1978-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023393-B2 Polymerizable 4,4′-spirobi[chromane]-2,2′-diones and curable compositions including the same CTRB2, CBR1, CCNB3 ALOX15 2157/4885POLB 1452/4885ALDH1A1 756/4885
US-20240122815-A1 POLYMERIZABLE 4,4'-SPIROBI[CHROMANE]-2,2'-DIONES AND CURABLE COMPOSITIONS INCLUDING THE SAME CTRB2, CBR1, CCNB3 ALOX15 2122/4885POLB 1553/4885ALDH1A1 718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.