SCHEMBL581815

SCHEMBL581815

Oc1c(Br)ccc(Br)c1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
RECQL P46063 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
APEX1 P27695 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
ALOX15 P16050 6/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28414394 0.82 CA1 (0.47) CA1CA2CA4CA6ALDH1A1
SCHEMBL30363595 0.82 CA1 (0.47) CA1CA2CA4CA6ALDH1A1
SCHEMBL69651 0.81 ALOX15 (0.42) CA1CA2CA4CA6ALDH1A1
SCHEMBL16431772 0.81 CA1 (0.43) CA1CA2CA4CA6ALDH1A1
SCHEMBL69425 0.81 CA1 (0.43) CA1CA2CA4CA6ALDH1A1
SCHEMBL374724 0.77 AKR1B1 (0.36) CA1CA2CA4CA6ALDH1A1
SCHEMBL5319019 0.77 CA1 (0.40) CA1CA2CA4CA6ALDH1A1
SCHEMBL11611309 0.77 ALDH1A1 (0.38) CA1CA2CA4CA6ALDH1A1
SCHEMBL29761144 0.77 AKR1B1 (0.36) CA1CA2CA4CA6ALDH1A1
SCHEMBL9153891 0.77 ALDH1A1 (0.36) CA1CA2CA4CA6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112946121-B Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2023-04-11 CN claimed
CN-112946121-A Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2021-06-11 CN claimed
EP-1543061-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-06-22 EP claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
WO-2004016674-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-20230398517-A1 NOVEL FORMO-PHENOLIC RESINS, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAME IN THE EXTRACTION OF URANIUM FROM WATER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2023-12-14 US disclosed
EP-4232491-A1 NOVEL FORMO-PHENOLIC RESINS, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAME IN THE EXTRACTION OF URANIUM FROM WATER Centre National de la Recherche Scientifique (CNRS) (FR) 2023-08-30 EP disclosed
CN-112946121-B Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2023-04-11 CN disclosed
WO-2022090242-A1 NOVEL FORMO-PHENOLIC RESINS, PROCESS FOR THE PREPARATION THEREOF, AND USE OF SAME IN THE EXTRACTION OF URANIUM FROM WATER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-05-05 WO disclosed
CN-112946121-A Method for determining monomer carbon stable isotope of bromophenol and application thereof 广东工业大学 2021-06-11 CN disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed
US-4172932-A Process for the preparation of polymers of cyclopentene or copolymers of cyclopentene with unsaturated alicyclic compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-10-30 US disclosed
US-4170614-A HYDROLYSIS OF TRIS(2,6-DIHALOPHENYL) PHOSPHATE PPG INDUSTRIES, INC. (US) 1979-10-09 US disclosed
US-4115364-A MELT SPINNING WITH A THERMOPLASTIC NYLON, CURING, REACTING WITH UREA COMPOUND NIPPON KYNOL INCORPORATED (JP) 1978-09-19 US disclosed
US-4059655-A REACTING A 2,6-DIHALOPHENOL WITH PHOSPHORUS OXYHALIDE, HYDROLYSIS PPG INDUSTRIES, INC. (US) 1977-11-22 US disclosed
US-3961123-A SULFONATED NOVOLAKS CONTAINING METAL ATOMS KANEBO, LTD. (JA) 1976-06-01 US disclosed