Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976701 | 0.94 | PTGER1 (0.42) | MGLLPTGDR2PTGER1 | |
| SCHEMBL6973204 | 0.91 | MEN1 (0.39) | MGLLPTGDR2PTGER1 | |
| SCHEMBL6969877 | 0.91 | MCHR1 (0.39) | MGLLPTGDR2PTGER1 | |
| Hydrochloric Acid SCHEMBL6977813 | 0.90 | MEN1 (0.38) | MGLLPTGDR2PTGER1 | |
| SCHEMBL6968399 | 0.89 | KMT2A (0.40) | MGLLPTGDR2PTGER1 | |
| SCHEMBL6967737 | 0.87 | MGLL (0.36) | MGLLPTGDR2PTGER1 | |
| SCHEMBL6977878 | 0.86 | KDM4E (0.40) | PTGER1 | |
| Hydrochloric Acid SCHEMBL6969218 | 0.85 | KDM4E (0.39) | PTGER1 | |
| SCHEMBL6974047 | 0.84 | PTGER1 (0.37) | MGLLPTGER1 | |
| SCHEMBL6967538 | 0.83 | HTR1A (0.37) | MGLLPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566376-B1 | For therapy of chemokine receptor related diseases and conditions such as rheumatoid arthritis, chronic obstructive pulmonary disease | ASTRAZENECA UK LIMITED (GB) | 2003-05-20 | — | — | US | claimed |
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |
| US-6566376-B1 | For therapy of chemokine receptor related diseases and conditions such as rheumatoid arthritis, chronic obstructive pulmonary disease | ASTRAZENECA UK LIMITED (GB) | 2003-05-20 | — | — | US | disclosed |
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | disclosed |