SCHEMBL6965264

SCHEMBL6965264

CC(=O)NC(C)c1ccc(OC(C)=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACACB O00763 20/20 0.60
ACACA Q13085 8/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4446314 0.84 ACACB (0.82) ACACBACACA
SCHEMBL4446311 0.84 ACACB (0.82) ACACBACACA
SCHEMBL16481118 0.82 ACACB (0.60) ACACBACACA
SCHEMBL12001658 0.79 ACACB (0.75) ACACBACACA
SCHEMBL7450674 0.79 MAPT (0.51) ACACBACACA
SCHEMBL12475738 0.79 ACACB (0.86) ACACBACACA
SCHEMBL29401218 0.79 MAPT (0.51) ACACBACACA
SCHEMBL11698235 0.79 MAPT (0.51) ACACBACACA
SCHEMBL1714626 0.79 LMNA (0.59)
SCHEMBL9506851 0.79 LMNA (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015444-B1 PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP LTD (KR) 2003-05-28 EP disclosed
US-6352993-B1 ANTIULCER AGENTS YUHAN CORPORATION (KR) 2002-03-05 US disclosed
EP-1015444-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION, LTD. (KR) 2000-07-05 EP disclosed
WO-1998043968-A1 NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 1998-10-08 WO disclosed