Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967410 | 0.88 | KCNH3 (0.34) | KCNH3TRPC3TRPC6MEN1KMT2A | |
| SCHEMBL6954449 | 0.87 | NOTUM (0.36) | KCNH3TRPC3TRPC6MEN1KMT2A | |
| SCHEMBL6967711 | 0.86 | TRPC3 (0.37) | KCNH3TRPC3TRPC6MEN1KMT2A | |
| SCHEMBL6964419 | 0.86 | KLK7 (0.40) | KCNH3RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6962395 | 0.85 | GAA (0.36) | KCNH3TRPC3TRPC6KMT2ARAB9A | |
| SCHEMBL6967941 | 0.85 | TRPC3 (0.34) | KCNH3TRPC3TRPC6MEN1KMT2A | |
| SCHEMBL6963603 | 0.84 | KCNH3 (0.36) | KCNH3POLBMEN1KMT2ARAB9A | |
| SCHEMBL6963630 | 0.84 | GAA (0.36) | KCNH3TRPC3TRPC6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6967875 | 0.84 | KDM4E (0.38) | KCNH3POLBMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL6961096 | 0.84 | KDM4E (0.34) | KCNH3TRPC3TRPC6BLMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |
| EP-1015444-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION, LTD. (KR) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998043968-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1998-10-08 | — | — | WO | disclosed |