Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 5/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963679 | 0.92 | POLB (0.40) | KCNH3LMNAMAPTL3MBTL1 | |
| SCHEMBL6967410 | 0.88 | KCNH3 (0.34) | ALDH1A1MAPK1SMN1; SMN2KCNH3LMNA | |
| SCHEMBL6954449 | 0.87 | NOTUM (0.36) | ALDH1A1SMN1; SMN2KCNH3LMNAGAA | |
| SCHEMBL6967711 | 0.86 | TRPC3 (0.37) | MAPK1KCNH3LMNANPSR1 | |
| SCHEMBL6965503 | 0.86 | KCNH3 (0.36) | SMN1; SMN2RAB9AKCNH3MAPTL3MBTL1 | |
| SCHEMBL6957770 | 0.85 | THRB (0.35) | KCNH3 | |
| SCHEMBL6962395 | 0.85 | GAA (0.36) | ALDH1A1SMN1; SMN2RAB9AKCNH3GAA | |
| SCHEMBL6967941 | 0.85 | TRPC3 (0.34) | MAPK1SMN1; SMN2KCNH3LMNANPSR1 | |
| SCHEMBL6963630 | 0.84 | GAA (0.36) | ALDH1A1SMN1; SMN2RAB9AKCNH3LMNA | |
| SCHEMBL6963603 | 0.84 | KCNH3 (0.36) | ALDH1A1MAPK1SMN1; SMN2RAB9AKCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |