Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041995 | 0.82 | TPMT (0.56) | TPMTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6672858 | 0.82 | TPMT (0.56) | TPMTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6959263 | 0.81 | PARP1 (0.57) | KMT2AALDH1A1RAB9AALOX15GAA | |
| SCHEMBL3595404 | 0.80 | TPMT (0.54) | TPMTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL588343 | 0.78 | ALDH1A1 (0.62) | TPMTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29236450 | 0.78 | TPMT (0.52) | TPMTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6966147 | 0.78 | CES2 (0.54) | MEN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL3062001 | 0.78 | TPMT (0.46) | TPMTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL6967629 | 0.76 | S1PR2 (0.43) | MEN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL2335900 | 0.75 | TPMT (0.48) | TPMTMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |