Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828069 | 0.84 | KDM4E (0.44) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL6961965 | 0.83 | NPC1 (0.41) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL18623686 | 0.83 | NPC1 (0.50) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL724170 | 0.78 | ALDH1A1 (0.43) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL15719546 | 0.78 | ALDH1A1 (0.43) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL691738 | 0.77 | HTT (0.44) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL23716391 | 0.76 | MAPT (0.40) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL20020213 | 0.74 | ALDH1A1 (0.47) | EPHX2NPC1RAB9AGAAALDH1A1 | |
| SCHEMBL6964641 | 0.73 | NOTUM (0.58) | NPC1RAB9AGAAALDH1A1MAPT | |
| SCHEMBL2824498 | 0.72 | ALDH1A1 (0.46) | EPHX2NPC1GAAALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |