Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974393 | 0.82 | CYP3A4 (0.38) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL6976691 | 0.78 | LIMK1 (0.38) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL6973287 | 0.77 | ALDH1A1 (0.45) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL6977794 | 0.71 | ALDH1A1 (0.37) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL24883082 | 0.70 | PRKCQ (0.43) | CYP2C19CYP3A4 | |
| SCHEMBL29286036 | 0.70 | RAB9A (0.56) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL30366154 | 0.70 | RAB9A (0.56) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL6777807 | 0.69 | NOTUM (0.48) | ALDH1A1SLC22A12KDM4EL3MBTL1CYP17A1 | |
| SCHEMBL6972704 | 0.68 | CFTR (0.41) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL8199590 | 0.67 | ALDH1A1 (0.37) | CYP2C19CYP3A4CYP2D6ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555501-B1 | Such as 5-methyl-2-(4-trifluoromethyl-3-pyridyl)-oxazole having improved toxicity in controlling insects and spider mites | HOECHST SCHERING AGREVO GMBH (DE) | 2003-04-29 | — | — | US | disclosed |
| EP-1140921-B1 | 4-TRIFLUOROMETHYL-3-OXAZOLYLPYRIDINES, METHOD FOR PRODUCING THEM, PRODUCTS CONTAINING THE SAME, AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-04-02 | — | — | EP | disclosed |
| EP-1140921-A1 | 4-TRIFLUOROMETHYL-3-OXAZOLYLPYRIDINES, METHOD FOR PRODUCING THEM, PRODUCTS CONTAINING THE SAME, AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035912-A1 | 4-TRIFLUOROMETHYL-3-OXAZOLYLPYRIDINES, METHOD FOR PRODUCING THEM, PRODUCTS CONTAINING THE SAME, AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-06-22 | — | — | WO | disclosed |