SCHEMBL6966079

Cc1cc(C2CCN(S(=O)(=O)C(C)(C)C(=O)NO)CC2)ccc1-c1cccc(OCCN(C)C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MMP3	P08254	13/20	1.00

▸	MMP2	P08253	11/20	1.00

▸	MMP1	P03956	2/20	0.85

▸	MMP9	P14780	2/20	0.85

▸	MMP14	P50281	2/20	0.85

▸	HDAC6	Q9UBN7	1/20	0.40

▸	KDM4E	B2RXH2	2/20	0.36

▸	ALDH1A1	P00352	1/20	0.36

▸	LMNA	P02545	1/20	0.36

▸	MAOB	P27338	1/20	0.36

▸	CHRNB2	P17787	1/20	0.35

▸	CHRNA4	P43681	1/20	0.35

▸	ADORA2A	P29274	1/20	0.35

▸	FAAH	O00519	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6585851	0.92	MMP3 (1.00)	MMP3MMP2MMP1MMP9MMP14
SCHEMBL6437005	0.91	MMP2 (0.83)	MMP3MMP2MMP1MMP9MMP14
SCHEMBL6973528	0.91	MMP3 (1.00)	MMP3MMP2MMP1MMP9MMP14
SCHEMBL6586804	0.91	MMP3 (1.00)	MMP3MMP2MMP1MMP9MMP14
SCHEMBL6972635	0.90	MMP3 (1.00)	MMP3MMP2MMP1MMP9MMP14
Hydrochloric Acid SCHEMBL6971643	0.90	MMP3 (0.98)	MMP3MMP2MMP1MMP9MMP14
SCHEMBL6585076	0.90	MMP3 (1.00)	MMP3MMP2MMP1MMP9MMP14
Hydrochloric Acid SCHEMBL6962275	0.89	MMP3 (0.98)	MMP3MMP2MMP1MMP9MMP14
Dimethylamine SCHEMBL6974207	0.88	MMP3 (0.97)	MMP3MMP2MMP1MMP9MMP14
SCHEMBL6956464	0.85	MMP3 (0.81)	MMP3MMP2MMP1MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1181017-B1	METALLOPROTEASE INHIBITORS	PFIZER LTD (GB)	2003-04-16	—	—	EP	claimed