Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966308 | 1.00 | TRPV1 (0.34) | TRPV1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL6972322 | 0.76 | DRD3 (0.37) | — | |
| SCHEMBL6972325 | 0.76 | DRD3 (0.37) | — | |
| SCHEMBL6978373 | 0.76 | TRPV1 (0.35) | TRPV1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL22728221 | 0.70 | TYR (0.51) | TRPV1MTNR1AMTNR1B | |
| SCHEMBL23487414 | 0.67 | CYP2D6 (0.34) | TRPV1SLC6A4 | |
| SCHEMBL8124875 | 0.66 | ENPP1 (0.35) | TRPV1 | |
| SCHEMBL11338421 | 0.65 | SLC6A4 (0.40) | SLC6A4 | |
| SCHEMBL18664158 | 0.65 | TRPV1 (0.37) | TRPV1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL4075615 | 0.64 | ESR1 (0.54) | TRPV1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | disclosed |
| EP-1051413-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037635-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1999-07-29 | — | — | WO | disclosed |