Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075615 | 0.83 | ESR1 (0.54) | MEN1KMT2ATRPV1MTNR1AMTNR1B | |
| SCHEMBL827301 | 0.83 | HTR1A (0.50) | MAPTTP53HTTMTNR1AMTNR1B | |
| SCHEMBL825930 | 0.79 | MTNR1A (0.40) | MTNR1AMTNR1BROCK2 | |
| SCHEMBL2237676 | 0.78 | LOXL2 (0.56) | CYP3A4ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL30665033 | 0.78 | LOXL2 (0.56) | CYP3A4ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL18664271 | 0.77 | TRPV1 (0.37) | TYRTRPV1MTNR1AMTNR1BESR1 | |
| SCHEMBL29032188 | 0.76 | MTNR1A (0.71) | CYP3A4MAPTTRPV1MTNR1AMTNR1B | |
| SCHEMBL30448603 | 0.76 | MTNR1A (0.71) | CYP3A4MAPTTRPV1MTNR1AMTNR1B | |
| SCHEMBL2364501 | 0.73 | LOXL2 (0.55) | CYP3A4MAPTALDH1A1GAAKDM4E | |
| SCHEMBL14394991 | 0.73 | CCR1 (0.55) | CYP3A4HTTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349586-B1 | ANTIFUNGAL COMPOUND PROCESS | MYCOVIA PHARMACEUTICALS INC (US) | 2020-12-02 | — | — | EP | disclosed |