Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | BCL6 | P41182 | 1/20 | 0.50 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830208 | 0.82 | ALDH1A1 (0.51) | MAPTALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL4829895 | 0.81 | MAPT (0.57) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14929541 | 0.80 | SMN1; SMN2 (0.57) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2311231 | 0.80 | MAPT (0.50) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2938667 | 0.79 | MEN1 (0.54) | MAPTALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL11086969 | 0.79 | ALDH1A1 (0.74) | MAPTALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL3670571 | 0.77 | TOP2A (0.53) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6969883 | 0.77 | MAPT (0.59) | MAPTKDM4EALDH1A1BCL6BCOR | |
| SCHEMBL6954918 | 0.77 | MAPT (0.69) | MAPTKDM4EALDH1A1KMT2ABCL6 | |
| SCHEMBL6891724 | 0.77 | TOP2A (0.46) | MAPTALDH1A1SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |