Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974490 | 0.98 | SHBG (0.39) | SHBGCA12CA1CA2MMP2 | |
| SCHEMBL3860886 | 0.92 | — | — | |
| SCHEMBL6973956 | 0.83 | CA12 (0.39) | SHBGCA12CA1CA2MMP2 | |
| SCHEMBL6976069 | 0.82 | CA12 (0.42) | SHBGCA12CA1CA2MMP2 | |
| SCHEMBL6970474 | 0.77 | SHBG (0.33) | SHBG | |
| SCHEMBL6965872 | 0.76 | SHBG (0.36) | SHBGEPHX1 | |
| SCHEMBL1043899 | 0.73 | — | — | |
| SCHEMBL7846367 | 0.72 | NISCH (0.32) | — | |
| SCHEMBL6976498 | 0.72 | CA12 (0.42) | SHBGCA12CA1CA2MMP2 | |
| SCHEMBL6963012 | 0.70 | CA12 (0.46) | SHBGCA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |