SCHEMBL6974490

SCHEMBL6974490

CCC[CH]NC(C)C1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.39
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
MMP2 P08253 2/20 0.36
CA9 Q16790 2/20 0.36
EPHX1 P07099 3/20 0.34
DAPK3 O43293 1/20 0.31
ROCK2 O75116 1/20 0.31
CHEK2 O96017 1/20 0.31
PIM1 P11309 1/20 0.31
PLK1 P53350 1/20 0.31
ROCK1 Q13464 1/20 0.31
CDC42BPA Q5VT25 1/20 0.31
AURKB Q96GD4 1/20 0.31
PLK3 Q9H4B4 1/20 0.31
MAPKAPK2 P49137 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CNR2 P34972 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6966593 0.98 SHBG (0.35) SHBGCA12CA1CA2MMP2
SCHEMBL3860886 0.90
SCHEMBL6976069 0.84 CA12 (0.42) SHBGCA12CA1CA2MMP2
SCHEMBL6973956 0.82 CA12 (0.39) SHBGCA12CA1CA2MMP2
SCHEMBL6965872 0.78 SHBG (0.36) SHBGEPHX1SMN1; SMN2
SCHEMBL6970474 0.76 SHBG (0.33) SHBGSMN1; SMN2
SCHEMBL6963012 0.73 CA12 (0.46) SHBGCA12CA1CA2MMP2
SCHEMBL1043899 0.71
SCHEMBL7846367 0.71 NISCH (0.32)
SCHEMBL13075595 0.71 CA12 (0.40) SHBGCA12CA1CA2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed