Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973956 | 0.98 | CA12 (0.39) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6974490 | 0.84 | SHBG (0.39) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6966593 | 0.82 | SHBG (0.35) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6973973 | 0.78 | SHBG (0.45) | SHBGEPHX1TP53KDM4E | |
| SCHEMBL6963012 | 0.76 | CA12 (0.46) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6975537 | 0.75 | SHBG (0.41) | SHBGEPHX1TP53 | |
| SCHEMBL13075595 | 0.74 | CA12 (0.40) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL8952012 | 0.74 | ADH1B (0.46) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL182149 | 0.74 | ADH1B (0.46) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL6976498 | 0.73 | CA12 (0.42) | CA12CA1CA2MMP2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |