Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967192 | 0.91 | LTA4H (0.47) | LTA4HTDP1HTTHRH1DRD1 | |
| SCHEMBL6960995 | 0.86 | LTA4H (0.42) | LTA4HTDP1HTTHRH1DRD1 | |
| SCHEMBL7819929 | 0.81 | S1PR1 (0.38) | LTA4HHTTHRH3KCNH2MCHR1 | |
| SCHEMBL6963429 | 0.81 | LTA4H (0.56) | LTA4HHTTHRH1DRD1DRD4 | |
| SCHEMBL7818684 | 0.81 | DRD2 (0.41) | LTA4HDRD4DRD2HRH3MCHR1 | |
| SCHEMBL7445212 | 0.80 | F2 (0.46) | LTA4HTDP1HTTHRH1DRD1 | |
| SCHEMBL8127544 | 0.80 | POLB (0.43) | LTA4HHTT | |
| SCHEMBL7818112 | 0.78 | S1PR1 (0.47) | HRH3MCHR1 | |
| SCHEMBL7346673 | 0.77 | LTA4H (0.54) | LTA4HHTTHRH3KCNH2MCHR1 | |
| SCHEMBL7818690 | 0.74 | S1PR1 (0.39) | HRH3MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |