Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 9/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962831 | 0.95 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL6968168 | 0.91 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL6961149 | 0.89 | P2RX3 (0.35) | P2RX3PPARGKCNH2ALDH1A1TDP1 | |
| SCHEMBL6971990 | 0.88 | PPARG (0.34) | P2RX3PPARGKCNH2 | |
| SCHEMBL7081431 | 0.85 | P2RX3 (0.33) | P2RX3PPARGKCNH2 | |
| SCHEMBL7083336 | 0.84 | ALDH1A1 (0.34) | PPARGKCNH2ALDH1A1TDP1AGTR1 | |
| SCHEMBL7079248 | 0.84 | TDP1 (0.37) | PPARGALDH1A1TDP1AGTR1AGTR2 | |
| SCHEMBL7087497 | 0.84 | P2RX3 (0.36) | P2RX3PPARGKCNH2ALDH1A1TDP1 | |
| SCHEMBL6970500 | 0.83 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL6969774 | 0.83 | ENPP2 (0.35) | ALDH1A1TDP1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |