Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973759 | 0.80 | TP53 (0.36) | MEN1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL6968903 | 0.78 | MEN1 (0.43) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL96828 | 0.74 | LMNA (0.53) | MEN1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL6973951 | 0.73 | MEN1 (0.37) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL7081015 | 0.72 | MEN1 (0.36) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL14439848 | 0.71 | POLB (0.46) | MEN1KMT2APOLBSMN1; SMN2HTT | |
| SCHEMBL6973406 | 0.71 | KDM4E (0.36) | MEN1KMT2APOLBMAPTTLR7 | |
| SCHEMBL10836880 | 0.70 | TSHR (0.51) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL97080 | 0.70 | LMNA (0.55) | MEN1KMT2ALMNAPOLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10838096 | 0.69 | TSHR (0.50) | MEN1KMT2ALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |