Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439852 | 0.87 | TLR7 (0.35) | POLBMEN1KMT2A | |
| SCHEMBL14439853 | 0.85 | MEN1 (0.32) | POLBMEN1KMT2ATDP1 | |
| SCHEMBL14439846 | 0.84 | PLA2G2A (0.48) | TDP1SMN1; SMN2ALDH1A1HPGDPLA2G2A | |
| SCHEMBL6967543 | 0.82 | TDP1 (0.38) | POLBMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL6966848 | 0.82 | TDP1 (0.42) | POLBMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL14439849 | 0.81 | PLA2G2A (0.41) | POLBMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL6962108 | 0.81 | TDP1 (0.37) | POLBMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7078348 | 0.80 | SMN1; SMN2 (0.36) | POLBMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL6975192 | 0.80 | TDP1 (0.43) | POLBMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6968903 | 0.80 | MEN1 (0.43) | POLBMEN1KMT2ATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |
| US-20070190523-A1 | Method and compositions for identifying anti-hiv therapeutic compounds | GILEAD SCIENCES, INC. | 2007-08-16 | — | — | US | disclosed |