Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962178 | 0.89 | LMNA (0.40) | MEN1KMT2ALMNATDP1SMN1; SMN2 | |
| SCHEMBL6969647 | 0.87 | TLR7 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL14439848 | 0.80 | POLB (0.46) | MEN1KMT2ATDP1POLBSMN1; SMN2 | |
| SCHEMBL6973410 | 0.79 | LMNA (0.41) | LMNATDP1POLBSMN1; SMN2MAPT | |
| SCHEMBL6966931 | 0.78 | MEN1 (0.43) | MEN1KMT2ALMNATDP1POLB | |
| SCHEMBL6972595 | 0.77 | LMNA (0.48) | LMNA | |
| SCHEMBL6966848 | 0.73 | TDP1 (0.42) | MEN1KMT2ATDP1POLBTP53 | |
| SCHEMBL6962108 | 0.72 | TDP1 (0.37) | MEN1KMT2ALMNATDP1POLB | |
| SCHEMBL6975192 | 0.71 | TDP1 (0.43) | MEN1KMT2ALMNATDP1POLB | |
| SCHEMBL7078348 | 0.71 | SMN1; SMN2 (0.36) | MEN1KMT2ATDP1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |