Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971704 | 0.79 | GAA (0.35) | GAAALDH1A1HPGDNPSR1TDP1 | |
| SCHEMBL158021 | 0.79 | GAA (0.41) | POLBMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL6967216 | 0.77 | POLB (0.42) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL10973768 | 0.77 | POLB (0.67) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL6971199 | 0.75 | NPSR1 (0.34) | CYP1A2CYP2C19GAAALDH1A1HPGD | |
| SCHEMBL6965156 | 0.72 | MAPT (0.48) | POLBKMT2AGAAMAPTALDH1A1 | |
| SCHEMBL1490709 | 0.69 | L3MBTL1 (0.55) | POLBKMT2AGAAALDH1A1HPGD | |
| SCHEMBL6971606 | 0.69 | — | — | |
| SCHEMBL687760 | 0.68 | MAPT (0.46) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL8994450 | 0.67 | ALDH1A1 (0.35) | POLBMEN1KMT2ACYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |