Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967347 | 1.00 | MAPT (0.35) | MAPTGAAALDH1A1GHSRKMT2A | |
| SCHEMBL6962849 | 0.95 | MAPT (0.35) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6962845 | 0.95 | MAPT (0.35) | MAPTGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL6963186 | 0.88 | SCN9A (0.39) | MAPTGAAALDH1A1GHSRRORC | |
| SCHEMBL6963190 | 0.88 | SCN9A (0.39) | MAPTGAAALDH1A1GHSRRORC | |
| SCHEMBL6962957 | 0.87 | KMT2A (0.35) | MAPTKMT2AMEN1RORCEGFR | |
| SCHEMBL6967090 | 0.87 | SCN9A (0.34) | MAPTGAAALDH1A1GHSRRORC | |
| SCHEMBL6964322 | 0.87 | ALDH1A1 (0.40) | MAPTGAAALDH1A1GHSRKMT2A | |
| SCHEMBL6965678 | 0.87 | PABPC1 (0.41) | HDAC8NPR3 | |
| SCHEMBL6965676 | 0.87 | PABPC1 (0.41) | HDAC8NPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |