Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972175 | 0.89 | TAAR1 (0.40) | GRIN2BGRIN1HRH4HRH3ATP4A | |
| SCHEMBL6973014 | 0.85 | GRIN2B (0.55) | GRIN2BGRIN1NOS2 | |
| SCHEMBL6973473 | 0.83 | GRIN2B (0.39) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL649075 | 0.78 | ALDH1A1 (0.46) | HRH4HRH3ALDH1A1 | |
| SCHEMBL6974030 | 0.78 | TAAR1 (0.40) | GRIN2BGRIN1HRH4HRH3ATP4A | |
| SCHEMBL6831177 | 0.77 | GRIN2B (0.66) | GRIN2BGRIN1HIF1ANOS2GRIN2D | |
| SCHEMBL6968578 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN1SIGMAR1HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL4737688 | 0.75 | GRIN2B (0.63) | GRIN2BGRIN1HIF1ANOS2GRIN2D | |
| SCHEMBL6961034 | 0.75 | GRIN2B (0.57) | GRIN2BGRIN1HIF1ASLC22A2HRH4 | |
| SCHEMBL6973872 | 0.73 | GRIN2B (0.40) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |