Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973473 | 0.90 | GRIN2B (0.39) | TAAR1HSP90AB1HRH3HRH4TP53 | |
| SCHEMBL6974030 | 0.89 | TAAR1 (0.40) | TAAR1HRH3HRH4TP53CYP1A2 | |
| SCHEMBL6967752 | 0.89 | GRIN2B (0.42) | HRH3HRH4GRIN2BGRIN1ATP4A | |
| SCHEMBL6968578 | 0.88 | GRIN2B (0.46) | TAAR1HSP90AB1HRH3HRH4TP53 | |
| SCHEMBL6955812 | 0.85 | GRIN2B (0.55) | TAAR1HSP90AB1GRIN2BGRIN1 | |
| SCHEMBL11047959 | 0.81 | HSP90AB1 (0.47) | TAAR1HSP90AB1 | |
| SCHEMBL6972183 | 0.79 | GRIN2B (0.47) | TAAR1HRH3HRH4TP53CYP1A2 | |
| SCHEMBL6970991 | 0.78 | GRIN2B (0.51) | TAAR1GRIN2BGRIN1HTR3EHTR3B | |
| SCHEMBL6968016 | 0.77 | GRIN2B (0.37) | TAAR1HSP90AB1HRH3HRH4TP53 | |
| SCHEMBL6968091 | 0.74 | GRIN2B (0.53) | TAAR1HRH3HRH4TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | claimed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |