Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966150 | 0.83 | POLB (0.49) | ARGAAPOLBALDH1A1MAPT | |
| SCHEMBL2268413 | 0.79 | TEAD4 (0.41) | ARGAAPOLBALDH1A1TEAD4 | |
| SCHEMBL22199026 | 0.77 | AR (0.63) | ARGAAPOLBCYP1A2SLC22A12 | |
| SCHEMBL29681639 | 0.77 | GAA (0.74) | ARGAAPOLBCYP1A2 | |
| SCHEMBL9590630 | 0.77 | GAA (0.74) | ARGAAPOLBCYP1A2 | |
| SCHEMBL13074158 | 0.77 | AR (0.62) | ARGAAPOLBCYP1A2ALDH1A1 | |
| SCHEMBL5583577 | 0.76 | HTR2A (0.42) | ARPOLBALDH1A1TEAD4MAPT | |
| SCHEMBL5583633 | 0.76 | AR (0.51) | ARGAAPOLBALDH1A1TEAD4 | |
| SCHEMBL230031 | 0.74 | ALDH1A1 (0.48) | ARGAAPOLBALDH1A1 | |
| SCHEMBL9685431 | 0.72 | TEAD4 (0.38) | ARPOLBALDH1A1TEAD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |