Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4242219 | 0.84 | ALDH1A1 (0.46) | ARALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL11653814 | 0.84 | L3MBTL1 (0.46) | ARALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL5448722 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1HTTL3MBTL1MEN1 | |
| SCHEMBL2268413 | 0.81 | TEAD4 (0.41) | ARALDH1A1HTTACHETEAD4 | |
| SCHEMBL9685431 | 0.79 | TEAD4 (0.38) | ARALDH1A1ACHETEAD4MEN1 | |
| SCHEMBL5583577 | 0.79 | HTR2A (0.42) | ARALDH1A1ACHETEAD4MEN1 | |
| SCHEMBL8674 | 0.78 | CA2 (0.46) | ALDH1A1MAPK1HTTL3MBTL1ACHE | |
| SCHEMBL10354935 | 0.77 | PTPRZ1 (0.39) | ARALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL2265983 | 0.76 | POLB (0.42) | ARALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL6305394 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPK1HTTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | claimed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | claimed |
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |