Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968026 | 1.00 | CHRNB2 (0.37) | CHRNB2CHRNA5CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL6963231 | 0.85 | FAAH (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL6963235 | 0.85 | FAAH (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL8522230 | 0.84 | KCNH2 (0.39) | CHRNB2CHRNA5CHRNA7CHRNA4KCNH2 | |
| SCHEMBL6976242 | 0.84 | FAAH (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4KCNH2 | |
| SCHEMBL6976244 | 0.84 | FAAH (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4KCNH2 | |
| SCHEMBL6969620 | 0.83 | PPARG (0.38) | CHRNB2CHRNA5CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL6973868 | 0.83 | PPARG (0.38) | CHRNB2CHRNA5CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL6963243 | 0.82 | FFAR1 (0.42) | KCNH2MCHR1HRH3MAPT | |
| SCHEMBL6967119 | 0.82 | FFAR1 (0.42) | KCNH2MCHR1HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894089-B9 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2003-04-02 | — | — | EP | disclosed |
| EP-0894089-B1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2002-10-23 | — | — | EP | disclosed |
| EP-0894089-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997041121-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING ANTIDIABETIC, HYPOLIPIDAEMIC, ANTIHYPERTENSIVE PROPERTIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |