Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960412 | 0.86 | GAA (0.43) | KMT2AMEN1L3MBTL1GAACA12 | |
| SCHEMBL6969104 | 0.74 | GAA (0.45) | KMT2AMEN1GAAGSR | |
| SCHEMBL6973924 | 0.73 | KMT2A (0.47) | KMT2AMEN1GAA | |
| SCHEMBL5741936 | 0.69 | GAA (0.55) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL6858351 | 0.69 | HSP90AB1 (0.59) | VCAM1KMT2AMEN1GAACA1 | |
| SCHEMBL20599232 | 0.69 | HSP90AB1 (0.51) | VCAM1KMT2AMEN1GAACA1 | |
| SCHEMBL7733874 | 0.68 | HDAC3 (0.49) | KMT2AMEN1GAA | |
| SCHEMBL14586752 | 0.67 | GAA (0.57) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL8340038 | 0.66 | GAA (0.73) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL11914171 | 0.65 | NAMPT (0.51) | KMT2AMEN1GAAANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785927-B1 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 2003-08-27 | — | — | EP | disclosed |
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| US-6365606-B1 | TREATMENT OF DISEASES WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF CYTOKINES; SIDE EFFECT REDUCTION; ISOINDOLES; BRONCHODILATOR; ANTI-INFLAMMATORY AGENT | EURO-CELTIQUE, S.A. (LU) | 2002-04-02 | — | — | US | disclosed |
| EP-1160247-A1 | 6,5-Fused aromatic ring systems having enhanced phosphodiesterae IV inhibitory activity | Euro-Celtique S.A. (LU) | 2001-12-05 | — | — | EP | disclosed |
| US-6075016-A | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity | EURO-CELTIQUE S.A. (LU) | 2000-06-13 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| US-5665737-A | PHOSPHODIESTERASE INHIBITORS | EURO-CELTIQUE, S.A. (LU) | 1997-09-09 | — | — | US | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |