Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | SELL | P14151 | 3/20 | 0.46 |
| ▸ | SELP | P16109 | 3/20 | 0.46 |
| ▸ | SELE | P16581 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735505 | 0.88 | GAA (0.62) | HPGDALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6973924 | 0.84 | KMT2A (0.47) | MAPTHPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8078098 | 0.80 | GAA (0.67) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL3661171 | 0.78 | TOP1 (0.57) | MAPTALDH1A1RAB9ANPC1GAA | |
| SCHEMBL11914171 | 0.77 | NAMPT (0.51) | ALDH1A1SMN1; SMN2NPC1GAAKMT2A | |
| SCHEMBL29511368 | 0.77 | HPGD (0.67) | HDAC3MAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4433540 | 0.77 | HPGD (0.67) | HDAC3MAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL14586752 | 0.77 | GAA (0.57) | MAPTHPGDALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL6969104 | 0.77 | GAA (0.45) | MAPTALDH1A1NFKB1GAASELL | |
| SCHEMBL7735192 | 0.76 | LMNA (0.41) | GAASELPSELEKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372770-B1 | TREATING A MAMMAL SUFFERING FROM A DISEASE STATE SELECTED FROM THE GROUP CONSISTING OF ASTHMA, ALLERGIES, INFLAMMATION, DEPRESSION, DEMENTIA, ATOPIC DISEASES, RHINITIS AND DISEASE STATES ASSOCIATED WITH ABNORMALLY HIGH PHYSIOLOGICAL LEVELS OF | EURO-CELTIQUE, S.A. | 2002-04-16 | — | — | US | disclosed |
| EP-0785927-A4 | NOVEL BENZOXAZOLES | EURO CELTIQUE SA (LU) | 1997-12-29 | — | — | EP | disclosed |
| EP-0785927-A1 | NOVEL BENZOXAZOLES | Euroceltique S.A. (LU) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011917-A1 | NOVEL BENZOXAZOLES | EURO-CELTIQUE, S.A. (LU) | 1996-04-25 | — | — | WO | disclosed |