Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | KCNK13 | Q9HB14 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969046 | 1.00 | ALDH1A1 (0.34) | ALDH1A1KDM4EALOX5APKCNK13TDP1 | |
| SCHEMBL6960641 | 0.89 | IDO1 (0.36) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL6960647 | 0.89 | IDO1 (0.36) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL8099986 | 0.89 | ALOX5AP (0.35) | ALDH1A1KDM4EALOX5APTDP1MAPT | |
| SCHEMBL8099988 | 0.89 | ALOX5AP (0.35) | ALDH1A1KDM4EALOX5APTDP1MAPT | |
| SCHEMBL6973384 | 0.88 | GRIN1 (0.36) | ALDH1A1KCNK13KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6973380 | 0.88 | GRIN1 (0.36) | ALDH1A1KCNK13KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6968696 | 0.88 | ACHE (0.35) | TDP1MEN1KMT2A | |
| SCHEMBL6968691 | 0.88 | ACHE (0.35) | TDP1MEN1KMT2A | |
| SCHEMBL6960954 | 0.87 | KCNK13 (0.30) | KCNK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |