Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960647 | 1.00 | IDO1 (0.36) | IDO1TDP1L3MBTL1MAPTTP53 | |
| SCHEMBL6968696 | 0.91 | ACHE (0.35) | IDO1TDP1ACHEKCNH2MEN1 | |
| SCHEMBL6968691 | 0.91 | ACHE (0.35) | IDO1TDP1ACHEKCNH2MEN1 | |
| SCHEMBL6966644 | 0.91 | ALDH1A1 (0.38) | IDO1TDP1L3MBTL1MAPTTP53 | |
| SCHEMBL6966647 | 0.91 | ALDH1A1 (0.38) | IDO1TDP1L3MBTL1MAPTTP53 | |
| SCHEMBL6973384 | 0.90 | GRIN1 (0.36) | IDO1TP53ALDH1A1HPGDHTT | |
| SCHEMBL6973380 | 0.90 | GRIN1 (0.36) | IDO1TP53ALDH1A1HPGDHTT | |
| SCHEMBL6969046 | 0.89 | ALDH1A1 (0.34) | TDP1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6969050 | 0.89 | ALDH1A1 (0.34) | TDP1MAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6969927 | 0.87 | IDO1 (0.38) | IDO1TDP1L3MBTL1TP53HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |