Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | CTH | P32929 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TPMT | P51580 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900728 | 0.88 | CA5A (0.48) | HMGB1CXCL12CTHCA1CA2 | |
| SCHEMBL454210 | 0.84 | HMGB1 (0.56) | HMGB1CXCL12CTHKDM4EALDH1A1 | |
| SCHEMBL348297 | 0.83 | CA1 (0.56) | HMGB1CXCL12CA12CA1CA2 | |
| SCHEMBL27690857 | 0.81 | CA1 (0.54) | HMGB1CXCL12CA12CA1CA2 | |
| SCHEMBL28766413 | 0.81 | CA1 (0.54) | HMGB1CXCL12CA12CA1CA2 | |
| SCHEMBL27998994 | 0.79 | CA1 (0.52) | HMGB1CXCL12CA12CA1CA2 | |
| SCHEMBL31238445 | 0.78 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6957335 | 0.78 | TTR (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1638962 | 0.78 | TTR (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12666445 | 0.78 | CA12 (0.43) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189504-A1 | BROAD - SPECTRUM ANTI VIRAL COMPOUNDS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2024-09-19 | — | — | WO | disclosed |
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6046212-A | ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |