SCHEMBL6900728

SCHEMBL6900728

CC(=O)c1cc(C)c(O)c(C(C)=O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.48
LMNA P02545 1/20 0.45
CTH P32929 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
NSD2 O96028 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
MCL1 Q07820 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
HSD17B1 P14061 1/20 0.38
AKR1C3 P42330 3/20 0.38
AKR1C2 P52895 3/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
ESR1 P03372 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6969296 0.88 HMGB1 (0.47) CA5ALMNACTHKDM4EMEN1
SCHEMBL454210 0.88 HMGB1 (0.56) CA5ALMNACTHKDM4EKMT2A
SCHEMBL13932440 0.86 CA5A (0.56) CA5ALMNAKDM4EMEN1KMT2A
SCHEMBL1644952 0.86 CA5A (0.56) CA5ALMNAMEN1KMT2AMAPT
SCHEMBL471443 0.80 KDM4E (0.46) LMNAKDM4EMEN1KMT2AHMGB1
SCHEMBL9753149 0.80 CA5A (0.44) CA5AKDM4EMEN1KMT2AHMGB1
SCHEMBL13144722 0.80 CA5A (0.50) CA5ALMNAKDM4EMEN1KMT2A
SCHEMBL18629882 0.78 CA5A (0.48) CA5ALMNAMEN1KMT2AMAPT
SCHEMBL30644001 0.77 KDM4E (0.44) CA5AKDM4EMEN1KMT2AHMGB1
SCHEMBL670721 0.77 KDM4E (0.44) CA5AKDM4EMEN1KMT2AHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1094056-B1 Process for the preparation of monoacetylated hydrochinone compounds BASF AG (DE) 2004-02-25 EP disclosed
US-6476253-B1 Process for preparing monoacetylated hydroquinone compounds BASF AKTIENGESELLSCHAFT (DE) 2002-11-05 US disclosed
EP-1094056-A1 Process for the preparation of monoacetylated hydrochinone compounds BASF AKTIENGESELLSCHAFT (DE) 2001-04-25 EP disclosed