Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970785 | 0.93 | LMNA (0.49) | TSHRLMNAALDH1A1KDM4EGAA | |
| SCHEMBL6968667 | 0.81 | HTR6 (0.48) | LMNAALDH1A1SMN1; SMN2HTR6AKR1C3 | |
| SCHEMBL6970750 | 0.80 | MAPT (0.47) | LMNASMN1; SMN2HTR6RORC | |
| SCHEMBL6970702 | 0.80 | HTR6 (0.47) | LMNAALDH1A1SMN1; SMN2HTR6AKR1C3 | |
| SCHEMBL6975027 | 0.79 | HTR6 (0.45) | ALDH1A1KDM4EHTR6AKR1C3 | |
| SCHEMBL6965033 | 0.77 | AKR1C3 (0.44) | LMNAALDH1A1KDM4EGAAHTR6 | |
| SCHEMBL6966090 | 0.77 | HTR6 (0.44) | HTR6AKR1C3 | |
| SCHEMBL6977499 | 0.76 | MAPT (0.55) | TSHRALDH1A1KDM4ESMN1; SMN2HTR6 | |
| SCHEMBL6968051 | 0.76 | AKR1C3 (0.46) | ALDH1A1GAAHTR6AKR1C3 | |
| SCHEMBL6975974 | 0.76 | AKR1C3 (0.48) | LMNAKDM4EHTR6AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |