Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.48 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965033 | 0.96 | AKR1C3 (0.44) | AKR1C3AKR1C2PTGESALOX5MAPT | |
| SCHEMBL6968051 | 0.95 | AKR1C3 (0.46) | AKR1C3AKR1C2PTGESALOX5HTR6 | |
| SCHEMBL6967437 | 0.91 | KMT2A (0.43) | AKR1C3AKR1C2PTGESALOX5MAPT | |
| SCHEMBL6967255 | 0.90 | AKR1C3 (0.42) | AKR1C3AKR1C2PTGESALOX5HTR6 | |
| SCHEMBL6975027 | 0.86 | HTR6 (0.45) | AKR1C3AKR1C2PTGESALOX5MAPT | |
| SCHEMBL6972542 | 0.84 | MAPT (0.47) | AKR1C3AKR1C2PTGESALOX5MAPT | |
| SCHEMBL6975922 | 0.83 | NPC1 (0.43) | AKR1C3AKR1C2PTGESALOX5MAPT | |
| SCHEMBL6968667 | 0.81 | HTR6 (0.48) | AKR1C3AKR1C2MAPTKMT2AHTR6 | |
| SCHEMBL6966615 | 0.81 | KMT2A (0.43) | AKR1C3AKR1C2MAPTKMT2AHTR6 | |
| SCHEMBL6970836 | 0.81 | PKM (0.40) | MAPTKMT2AHTR6L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |