Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967247 | 0.91 | POLB (0.38) | GAASMN1; SMN2POLBALDH1A1LMNA | |
| SCHEMBL6973145 | 0.78 | ALDH1A1 (0.40) | POLBALDH1A1 | |
| SCHEMBL6973013 | 0.78 | ALDH1A1 (0.40) | POLBALDH1A1 | |
| SCHEMBL6972441 | 0.76 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL6960549 | 0.75 | MAPT (0.38) | POLBALDH1A1NPSR1 | |
| SCHEMBL6968547 | 0.75 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL6969060 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL6970690 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6964253 | 0.74 | ALDH1A1 (0.34) | POLBALDH1A1 | |
| SCHEMBL6970684 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1LMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |