Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967247 | 0.75 | POLB (0.38) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6969494 | 0.75 | GAA (0.36) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1820575 | 0.69 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E | |
| SCHEMBL5696786 | 0.68 | MLYCD (0.69) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E | |
| SCHEMBL8247643 | 0.68 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E | |
| SCHEMBL3632818 | 0.66 | SMN1; SMN2 (0.86) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E | |
| SCHEMBL1820373 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AMLYCDMAPK1 | |
| SCHEMBL31541280 | 0.65 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E | |
| SCHEMBL1820817 | 0.65 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E | |
| SCHEMBL25942822 | 0.64 | MLYCD (0.59) | SMN1; SMN2NPC1RAB9AMLYCDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |