Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.58 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978209 | 0.84 | CNR1 (0.49) | KDM4ECYP1A2HRH3GUCY1B2CHRM2 | |
| SCHEMBL8808522 | 0.84 | KDM4E (0.82) | KDM4ECYP1A2HRH3GUCY1B2CHRM2 | |
| SCHEMBL6974448 | 0.83 | CNR1 (0.48) | KDM4ECYP1A2HRH3GUCY1B2CHRM2 | |
| SCHEMBL6969602 | 0.79 | CNR2 (0.52) | KDM4ECNR2CNR1ACHE | |
| SCHEMBL6969861 | 0.79 | CNR2 (0.44) | KDM4ECYP1A2HRH3GUCY1B2CHRM2 | |
| SCHEMBL6977954 | 0.78 | CNR2 (0.53) | KDM4ECYP1A2SLC6A4CNR2CNR1 | |
| SCHEMBL8809795 | 0.78 | MET (0.50) | KDM4ECYP1A2HRH3GUCY1B2CHRM2 | |
| SCHEMBL6966885 | 0.76 | KDM4E (0.50) | KDM4ECYP1A2HTR1APOLBCNR2 | |
| SCHEMBL9917395 | 0.76 | HRH3 (0.77) | KDM4ECYP1A2HRH3GUCY1B2CHRM2 | |
| SCHEMBL6968036 | 0.75 | CNR1 (0.49) | KDM4ECYP1A2POLBCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |