Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.51 |
| ▸ | CNR1 | P21554 | 9/20 | 0.51 |
| ▸ | ACHE | P22303 | 7/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970939 | 0.90 | CNR2 (0.47) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6970142 | 0.89 | CNR2 (0.54) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6969154 | 0.84 | CNR2 (0.54) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6971751 | 0.80 | CNR2 (0.41) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6969602 | 0.80 | CNR2 (0.52) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6973555 | 0.80 | ACHE (0.48) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6970884 | 0.79 | CNR2 (0.54) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6973326 | 0.79 | CNR2 (0.58) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6979206 | 0.78 | CNR2 (0.41) | CNR2CNR1ACHEBCHELMNA | |
| SCHEMBL6975698 | 0.78 | HTR6 (0.39) | CNR2CNR1ACHEPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |