Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.47 |
| ▸ | CNR1 | P21554 | 9/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975193 | 0.90 | CNR2 (0.51) | CNR2CNR1ACHEBCHEPIK3R1 | |
| SCHEMBL6971235 | 0.85 | CNR2 (0.47) | CNR2CNR1ACHEBCHEPIK3R1 | |
| SCHEMBL6970142 | 0.82 | CNR2 (0.54) | CNR2CNR1ACHEBCHEPIK3R1 | |
| SCHEMBL6969602 | 0.79 | CNR2 (0.52) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6969861 | 0.79 | CNR2 (0.44) | CNR2CNR1ACHEPIK3R1PIK3CA | |
| SCHEMBL6967696 | 0.78 | ACHE (0.44) | CNR2CNR1ACHEALDH1A1MAPT | |
| SCHEMBL6970884 | 0.76 | CNR2 (0.54) | CNR2CNR1ACHEBCHEPIK3R1 | |
| SCHEMBL6975124 | 0.76 | HTR6 (0.39) | ALDH1A1LMNAMAPT | |
| SCHEMBL6973555 | 0.76 | ACHE (0.48) | CNR2CNR1ACHEBCHEPIK3R1 | |
| SCHEMBL6969154 | 0.75 | CNR2 (0.54) | CNR2CNR1ACHEBCHEPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | disclosed |