Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23558112 | 0.75 | SMN1; SMN2 (0.65) | P2RX7ALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6956742 | 0.75 | ALDH1A1 (0.69) | LMNAALDH1A1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL5087248 | 0.75 | MAPK14 (0.68) | — | |
| SCHEMBL20037120 | 0.75 | KLK6 (0.81) | LMNAALDH1A1SMN1; SMN2RAB9AKLK6 | |
| SCHEMBL20551408 | 0.74 | HPGD (0.54) | P2RX7SMN1; SMN2CYP1A2CYP2C19KMT2A | |
| SCHEMBL6070540 | 0.74 | PDE4D (0.72) | ALDH1A1NPC1RAB9ANPSR1POLB | |
| SCHEMBL20037317 | 0.73 | LMNA (0.63) | P2RX7LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL20037308 | 0.73 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL6413900 | 0.71 | KMT2A (0.54) | LMNAALDH1A1KMT2AMEN1NOTUM | |
| SCHEMBL20037309 | 0.71 | LMNA (0.77) | LMNAALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |