SCHEMBL6969674

SCHEMBL6969674

O=c1cc[nH]c(=O)n1-c1cccc2ncsc12

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.41
OPRL1 P41146 1/20 0.41
CNOT7 Q9UIV1 1/20 0.33
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GOT1 P17174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965571 0.72 ELANE (0.34)
SCHEMBL26684317 0.70 CRBN (0.41) OPRM1OPRL1CNOT7
SCHEMBL7088425 0.70 OPRM1 (0.41) OPRM1OPRL1ALDH1A1HSD17B10
SCHEMBL26684312 0.69 CRBN (0.50) OPRM1OPRL1
SCHEMBL30688314 0.69 CRBN (0.50) OPRM1OPRL1
SCHEMBL8110269 0.67 ADRB1 (0.47) OPRM1OPRL1GOT1
SCHEMBL7229298 0.67 AHR (0.42)
SCHEMBL2576996 0.67 PDPK1 (0.52) CNOT7ALDH1A1HSD17B10
SCHEMBL11378918 0.66 MAPK8 (0.31)
SCHEMBL8695056 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624119-B1 Herbicidally active uracil compounds which allow better targeted control of undesirable plants than the known uracil compounds BASF AKTIENGESELLSCHAFT (DE) 2003-09-23 US disclosed
EP-1131319-B1 3- BENZ(OX/THI)AZOL-7-YL -1H-PYRIMIDINE-2,4-DIONES BASF AG (DE) 2003-09-03 EP disclosed
EP-1200428-B1 SUBSTITUTED BENZOXAZOLES BASF AG (DE) 2003-04-16 EP disclosed
EP-1200428-A1 SUBSTITUTED BENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2002-05-02 EP disclosed
CN-1330649-A Herbicidal-3-[benzo(ox/thi)azol-7-yl)-1H-pyrimidine-2,4-diones BASF AG (DE) 2002-01-09 CN disclosed
EP-1131319-A2 3- BENZ(OX/THI)AZOL-7-YL -1H-PYRIMIDINE-2,4-DIONES BASF AKTIENGESELLSCHAFT (DE) 2001-09-12 EP disclosed
WO-2001012625-A2 SUBSTITUTED BENZOXAZOLES BASF AKTIENGESELLSCHAFT (DE) 2001-02-22 WO disclosed
WO-2000028822-A2 HERBICIDAL 3-(BENZO(OX/THI)AZOL-7-YL)-1H-PYRIMIDINE-2,4-DIONES BASF AKTIENGESELLSCHAFT (DE) 2000-05-25 WO disclosed