Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969847 | 0.81 | NQO2 (0.47) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7919531 | 0.77 | MAPT (0.33) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7059454 | 0.74 | MEN1 (0.38) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9363731 | 0.74 | MAPT (0.32) | MAPT | |
| SCHEMBL8057087 | 0.74 | MAPT (0.38) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9522187 | 0.72 | KDM4E (0.44) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7603698 | 0.72 | MAPT (0.39) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6964915 | 0.70 | MAPT (0.35) | NPC1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29561649 | 0.69 | — | — | |
| SCHEMBL8485908 | 0.69 | PSMB8 (0.42) | NPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |