Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.31 |
| ▸ | ILK | Q13418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9087618 | 0.80 | MAPT (0.35) | MAPTPOLBSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7183586 | 0.80 | MAPT (0.37) | MAPTPOLBSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7243970 | 0.80 | PKM (0.37) | MAPTPOLBSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9089945 | 0.80 | NPC1 (0.44) | MAPTPOLBSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9087862 | 0.80 | TSHR (0.53) | MAPTPOLBSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL7685621 | 0.80 | ALDH1A1 (0.34) | MAPTPOLBSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9087787 | 0.80 | CYP3A4 (0.56) | MAPTSMN1; SMN2TP53ALDH1A1LMNA | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2TP53ALDH1A1LMNA | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL8588144 | 0.79 | MAPT (0.45) | MAPTPOLBSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL3743974 | 0.78 | PARP1 (0.40) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |